Frequently Asked Questions

Therapeutic plasma exchange (TPE) is a medical procedure that removes plasma from your blood and replaces it with a clean substitution fluid, typically albumin. It is performed under physician supervision using medical-grade apheresis equipment. The procedure separates blood components, discards the plasma, and returns your blood cells to your body.

The terms are often used interchangeably. Plasmapheresis is the general process of separating and removing plasma from the blood. Therapeutic plasma exchange (TPE) is a form of plasmapheresis in which the removed plasma is replaced with a substitution fluid such as albumin. At Plasma Life Center we perform TPE with albumin replacement under physician supervision.

Most patients describe only mild discomfort from IV placement, similar to a blood draw. During the session you remain seated in a recliner; many patients read or rest for the 1.5–3 hour treatment.

TPE is a well-established medical procedure performed in hospitals and outpatient clinics worldwide. Like all medical procedures, it carries some risks, including temporary fatigue, minor discomfort at the IV site, and rare allergic reactions to replacement fluids. Your physician will discuss all risks specific to your health profile during consultation.

A typical TPE session takes approximately 1.5 to 3 hours, depending on your protocol. Your physician will provide specific time estimates based on your individualized treatment plan.

The number of sessions varies by individual and depends on your condition, treatment goals, and how you respond to the procedure. Some patients may benefit from a short series; others may require ongoing sessions. Your physician will discuss a recommended protocol during consultation.

A physician referral is not required to request a consultation at Plasma Life Center. However, we welcome referrals from your existing healthcare providers and can coordinate care as needed.

Candidacy for TPE is determined on an individual basis through physician consultation. Factors include your medical history, current health status, specific condition or health goals, and whether the evidence supports TPE for your situation. Not every patient is a candidate.

Your physician will provide specific preparation instructions based on your protocol. General guidance typically includes staying well-hydrated, eating a light meal beforehand, and wearing comfortable clothing with accessible arms for IV placement. Avoid fasting unless specifically instructed.

Most patients can resume normal activities the same day. You may experience mild fatigue for a few hours. Your physician will provide specific aftercare instructions and let you know if there are any temporary precautions to observe.

We are a private pay and fee for service clinic and do not accept insurance.

Cost varies based on the treatment protocol, number of sessions, and individual factors. We discuss pricing and payment options during or after the initial consultation once a treatment plan is proposed. Please contact us directly for current information.

Plasma Life Center is located at 1785 San Carlos Ave, Suite 4, San Carlos, CA 94070. We are easily accessible from San Mateo, Redwood City, Belmont, and across the Peninsula, with convenient parking near downtown San Carlos.

You can request a consultation by calling (650) 289-8038 or by submitting a request through our contact page. We aim to respond within one business day.