Conditions & Topics
Therapeutic plasma exchange is discussed in the context of various conditions and health goals. The pages below are educational — they describe areas where TPE may be relevant, not a guarantee of candidacy or outcome.
Aging & Longevity Research
An emerging area of research where therapeutic plasma exchange and plasma dilution are being investigated for their potential to influence biological aging markers, based on parabiosis research and the Conboy laboratory studies.
Learn more →Allergy & Mast Cell Conditions
Therapeutic plasma exchange may help reduce IgE antibodies, histamine, and inflammatory mediators in mast cell activation syndrome (MCAS), chronic urticaria, and severe refractory allergies.
Learn more →Autoimmune & Neuroimmune Conditions
Therapeutic plasma exchange is an established treatment for autoimmune and neuroimmune conditions where pathogenic antibodies drive disease activity, including myasthenia gravis, lupus, MS, and PANS/PANDAS.
Learn more →Chronic Conditions
Exploring the role of therapeutic plasma exchange for chronic inflammatory conditions including long COVID, chronic fatigue syndrome (ME/CFS), and fibromyalgia, where persistent immune dysregulation may contribute to ongoing symptoms.
Learn more →Neurological Conditions
Therapeutic plasma exchange has established applications for neurological conditions including Guillain-Barré syndrome, CIDP, and neuropathies, with emerging research in Alzheimer's disease and cognitive decline.
Learn more →Our Approach to Condition Information
Every condition page on this site is reviewed by our clinical team before publication. We use a tiered evidence framework:
Conditions with recognized medical literature supporting TPE as a relevant intervention.
Areas where early or ongoing research suggests potential relevance, discussed with appropriate caution.
New to therapeutic plasma exchange? Learn how TPE works →
Want to Discuss a Specific Condition?
Our physician can discuss whether TPE may be relevant to your particular situation.
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