Over time, your blood accumulates toxins, inflammatory proteins, forever chemicals, and microplastics that impair organ function and accelerate aging. TPE removes your plasma — where these harmful substances live — and replaces it with fresh albumin, restoring balance and vitality.
A well-established medical procedure used for decades in hospital settings with an excellent safety profile.
Most patients experience little to no discomfort. The most common effects are mild fatigue and temporary tingling.
Every session is monitored by a board-certified physician and dedicated nursing staff from start to finish.
Each session takes approximately 1.5–3 hours. You sit comfortably while our technology does the work.
A gentle IV access point is established, and your blood is slowly drawn into our Terumo BCT Spectra Optia system — the gold standard in apheresis technology.
The machine spins your blood in a centrifuge, precisely separating plasma (which carries toxins and harmful proteins) from your red cells, white cells, and platelets.
Your old plasma is discarded and replaced with fresh albumin solution. Your cleaned blood — now free of accumulated toxins — is returned to your body.
Your plasma accumulates substances over a lifetime that your body cannot clear on its own. TPE mechanically removes them.
Chronic inflammation drives aging and disease. TPE clears inflammatory cytokines and autoantibodies that damage tissues throughout your body.
These synthetic compounds persist in your blood for years, disrupting hormones and immune function. TPE is one of the only ways to mechanically remove them.
Recent studies have found microplastics in human blood. These particles are linked to cellular stress. TPE filters them from your plasma.
Byproducts from medications, environmental pollutants, and metabolic waste that accumulate over time and impair organ function.
Senescent signaling molecules and damaged albumin that accelerate biological aging. Studies show TPE may lower epigenetic age markers.
In autoimmune conditions, the immune system produces harmful antibodies that attack healthy tissue. TPE directly removes them from circulation.
TPE has demonstrated benefits across a spectrum of conditions. We develop individualized treatment plans based on your specific diagnosis.
A landmark clinical trial found that therapeutic plasma exchange with albumin replacement may slow the decline of memory and daily functioning in patients with moderate Alzheimer's disease and mild cognitive impairment.
A clinical study reported that TPE lowered "biological age" estimates on epigenetic tests and improved multiple health-related blood markers — including inflammation and metabolism markers — for a sustained period after treatment.
Dr. Muharrem Yunce leads every treatment at Plasma Life Center. With advanced training from UCSF and Stanford University, he brings deep expertise in blood-based therapies and a commitment to personalized, evidence-based medicine.
TPE is a medical procedure that separates your blood plasma — where toxins, inflammatory proteins, and harmful substances accumulate — from your blood cells. The old plasma is discarded and replaced with fresh albumin solution. It's sometimes called "an oil change for your blood" because it mechanically removes what your body can't clear on its own.
The only discomfort is a brief needle pinch when IV access is established. Once connected, the procedure itself is painless. You can read, watch a show, or relax during the 1.5–3 hour session.
TPE has an excellent safety profile and is FDA-approved. It's been used in hospitals for decades. The most common short-term effects are mild fatigue, lightheadedness, or tingling — most patients experience little to no side effects. You're monitored continuously by a physician and nurse.
TPE is used for autoimmune diseases (lupus, MS, myasthenia gravis), neurological conditions (Alzheimer's, neuropathies, PANS/PANDAS), chronic conditions (Long COVID, chronic fatigue, fibromyalgia), and allergy-related disorders. It also supports anti-aging and longevity goals.
Frequency is highly individualized based on your condition, lab results, and treatment goals. During your free consultation, Dr. Yunce will design a tailored treatment plan specific to your needs.
